MEDICAL SECOND OPINION

Faculty of Medicine and Year of Graduation

Undergraduate Faculty of Medicine Cumhuriyet University 1990-1996

M.Sc. Faculty of Medicine Cumhuriyet University 1990-1996

Place and Year of Specialization Education

Doctorate / S.Efficiency / Specialization in Medicine Internal Medicine Kocaeli University 1998-2002

Minor Speciality (Medical Oncology) Medical Oncology Uludağ University 2008-2012

Associate Professor Title of Medical Oncology - 04.04.2016

Professional Experience

Research Assistant, Kocaeli University Medical Faculty Internal Diseases 1998-2002

Specialist Physcian (Internal Diseases) Kocaeli State Hospital 2002-2008

Minor Speciality Assistant Uludağ University Faculty of Medicine Medical Oncology BD 2008-2012

Physcian (Medical Oncology) Balıkesir State Hospital 2012-2014

Physcian (Medical Oncology) Ali Osman Sönmez Oncology Hospital 2014-2016

Associate Professor Nilüfer Avcı Balıkesir University Internal Diseases / Medical Oncology 2016-2017

Associate Professor Nilüfer Avcı Medikal Park Bursa, Medical Oncology 2017-2018

Associate Prof Dr Nilüfer Avcı Medicana Bursa, Medical Oncology 2018-

Medical Area of Interests

Cancer Types: Breast, Lung, Stomach, Pancreas, Safcomas, Prostate, Bladder

Cholarectol

Targeted treatments

Pain and nutrition therapy in cancer patients

Brain tumors

Scientific Publications

A. Articles published in international refereed journals:

A1. Avci N, Cecener G, Deligonul A, Erturk E, Tunca B, Egeli U, Tezcan G, Akyildiz EU, Bayram AS, Gebitekin C, Kurt E, Evrensel T. Molecular markers for patients with thymic malignancies: not feasible at present? Asian Pac J Cancer Prev.2014;15(8):3457-60. PubMed PMID: 24870739.

A2. Ulas A, Kos T, Avci N, Cubukcu E, Olmez OF, Bulut N, Degirmenci M. Patients with HER2-positive Early Breast Cancer Receiving Adjuvant Trastuzumab: Clinicopathological Features, Efficacy, and Factors Affecting Survival. Asian Pac J Cancer Prev. 2015;16(4):1643-9. PubMed PMID: 25743846.

A3. Kanat O, Cubukcu E, Avci N, Budak F, Ercan I, Canhoroz M, Olmez F. Comparison of three different treatment modalities in the management of cancer cachexia. Tumori. 2013 Mar-Apr;99(2):229-33. doi: 10.1700/1283.14197. PubMed PMID: 23748819.

A4. Avci N, Deligonul A, Tolunay S, Cubukcu E, Fatih Olmez O, Ulas A, Hartavi M, Kurt E, Evrensel T. Neoadjuvant chemotherapy-induced changes in immunohistochemical expression of estrogen receptor, progesterone receptor, HER2, and Ki-67 in patients with breast cancer. J BUON. 2015 Jan-Mar;20(1):45-9. PubMed PMID: 25778295.

A5. Avci N, Deligonul A, Tolunay S, Cubukcu E, Olmez OF, Altmısdortoglu O, Tanrıverdi O, Kurt E, Evrensel T. Prognostic impact of tumor lymphocytic infiltrates in patients with breast cancer undergoing neoadjuvant chemotherapy. J BUON. 2015 Jul-Aug;20(4):994-1000.

A6. Cubukcu E, Olmez OF, Avci N, Canhoroz M, Kurt E, Kanat O, Evrensel T, Manavoglu O. Identification of prognostic factors in patients with metastatic gastrointestinal stromal tumors. J BUON. 2012 Jul-Sep;17(3):517-21. PubMed PMID: 23033292

A7. Ulas A, Turkoz FP, Silay K, Tokluoglu S, Avci N, Oksuzoglu B, Alkis N. A laboratory prognostic index model for patients with advanced non-small cell lung cancer. PLoS One. 2014 Dec 4;9(12):e114471. doi: 10.1371/journal.pone.0114471. eCollection 2014. PubMed PMID: 25474743; PubMed Central PMCID: PMC4256446.

A8. Ulas A, Silay K, Akinci S, Dede DS, Akinci MB, Sendur MA, Cubukcu E, Coskun HS, Degirmenci M, Utkan G, Ozdemir N, Isikdogan A, Buyukcelik A, Inanc M, Bilici A, Odabasi H, Cihan S, Avci N, Yalcin B. Medication Errors in Chemotherapy Preparation and Administration: a Survey Conducted among Oncology Nurses in Turkey. Asian Pac J Cancer Prev. 2015;16(5):1699-705. PubMed PMID: 25773812.

A9. Tanriverdi O, Cokmert S, Oktay E, Pilanci KN, Menekse S, Kocar M, Sen CA, Avci N, Akman T, Ordu C, Goksel G, Meydan N. Prognostic significance of the baseline serum uric acid level in non-small cell lung cancer patients treated with first-line chemotherapy: a study of the Turkish Descriptive Oncological Researches Group. Med Oncol. 2014 Oct;31(10):217. doi: 10.1007/s12032-014-0217-z. Epub 2014 Sep 13. PubMed PMID: 25216865.

A10. Tanriverdi O, Yildirim B, Gul S, Cevik E, Akman T, Cokmert S, Pilanci KN, Avci N, Ordu C, Barutca S. Is there any effect of lower extremity deep vein thrombosis which proven by Doppler ultrasonography on cancer recurrence in patients with stage III colon cancer? A study of the Turkish Descriptive Oncological Researches Group. Med Oncol. 2014 Oct;31(10):215. doi: 10.1007/s12032-014-0215-1. Epub 2014 Sep 11. PubMed PMID: 25208817.

A11. Tanriverdi O, Kaytan-Saglam E, Ulger S, Bayoglu IV, Turker I, Ozturk-Topcu T, Cokmert S, Turhal S, Oktay E, Karabulut B, Kilic D, Kucukzeybek Y, Oksuzoglu B, Meydan N, Kaya V, Akman T, Ibis K, Saynak M, Sen CA, Uysal-Sonmez O, Pilancı KN, Demir G, Saglam S, Kocar M, Menekse S, Goksel G, Yapar-Taskoylu B, Yaren A, Uyeturk U, Avci N, Denizli B, Ilis-Temiz E. The clinical and pathological features of 133 colorectal cancer patients with brain metastasis: a multicenter retrospective analysis of the Gastrointestinal Tumors Working Committee of the Turkish Oncology Group (TOG). Med Oncol. 2014 Sep;31(9):152. doi: 10.1007/s12032-014-0152-z. Epub 2014 Aug 10. PubMed PMID: 25108599

A12. Yildiz I, Ekenel M, Akman T, Kocar M, Uysal M, Kanitez M, Varol U, Bayoglu IV, Tural D, Kaplan MA, Avci N, Sürmeli Z, Dede İ, Ulaş A, Yazici O, Basaran M. Sunitinib for patients with metastatic non-clear cell renal cell carcinoma: a Multicenter Retrospective Turkish Oncology Group trial. Anticancer Res. 2014 Aug;34(8):4329-34. PubMed PMID: 25075067.

A13. Canhoroz M, Kanat O, Saraydaroglu O, Buluc E, Avci N, Cubukcu E, Olmez OF, Manavoglu O. Clinical significance of adiponectin expression in colon cancer patients. J Cancer Res Ther. 2014 Apr-Jun;10(2):347-53. doi: 10.4103/0973-1482.136634. PubMed PMID: 25022390.

A14. Cecener G, Egeli U, Tunca B, Erturk E, Ak S, Gokgoz S, Tasdelen I, Tezcan G, Demirdogen E, Bayram N, Avci N, Evrensel T. BRCA1/2 germline mutations and their clinical importance in Turkish breast cancer patients. Cancer Invest. 2014 Oct;32(8):375-87. doi: 10.3109/07357907.2014.919302. Epub 2014 Jun 2. PubMed PMID: 24884828.

A15. Cubukcu E, Olmez OF, Kanat O, Kabul S, Canhoroz M, Avci N, Hartavi M, Deligonul A, Cubukçu S, Manavoglu O. Lack of prognostic significance of adiponectin immunohistochemical expression in patients with triple-negative breast cancer. Contemp Oncol (Pozn). 2014;18(1):34-8. doi: 10.5114/wo.2014.40454. Epub 2014 Feb 28. PubMed PMID: 24876819; PubMed Central PMCID: PMC4037995.

A16. Hartavi M, Kurt E, Oral B, Olmez OF, Cubukcu E, Deligonul A, Avci N, Manavoglu O. The SOCS-1 -1478CA/del polymorphism is not associated with colorectal cancer or age at onset in Turkish subjects. Asian Pac J Cancer Prev. 2013;14(12):7583-6. PubMed PMID: 24460337

A17. Uyeturk U, Tatli AM, Gucuk S, Oksuzoglu B, Ulas A, Avci N, Ozbay MF, Gunduz S, Akinci MB, Salim DK, Sonmez OU, Akdag F, Ergenc H. Risk factors for stage IV breast cancer at the time of presentation in Turkey. Asian Pac J Cancer Prev. 2013;14(12):7445-9. PubMed PMID: 24460317.

A18. Olmez OF, Evrensel T, Cubukcu E, Ugras N, Avci N, Canhoroz M, Deligonul A, Hartavi M, Olmez F, Cubukcu S, Tolunay S, Kurt E, Kanat O, Manavoglu O. Prognostic significance of human epidermal receptor (HER)- 3 immunohistochemical expression in patients with metastatic breast cancer. Asian Pac J Cancer Prev. 2013;14(7):4115-9. PubMed PMID: 23991962.

A19. Cubukcu E, Kanat O, Fatih Olmez O, Kabul S, Canhoroz M, Avci N, Deligonul A, Hartavi M, Cubukcu S, Olmez F, Kurt E, Evrensel T, Gokgoz S, Manavoglu O. Prognostic significance of estrogen receptor, progesterone receptor, HER2/neu, Ki-67, and nm23 expression in patients with invasive breast cancer. J BUON. 2013 Apr-Jun;18(2):359-65. PubMed PMID: 23818346

A20. Olmez OF, Cubukcu E, Evrensel T, Kurt M, Avci N, Tolunay S, Bekar A, Deligonul A, Hartavi M, Alkis N, Manavoglu O. The immunohistochemical expression of c-Met is an independent predictor of survival in patients with glioblastoma multiforme. Clin Transl Oncol. 2014 Feb;16(2):173-7. doi: 10.1007/s12094-013-1059-4. Epub 2013 Jun 6. PubMed PMID: 23740136

A21. Kurt E, Cubukcu E, Karabulut B, Olmez OF, Kurt M, Avci N, Ozdemir F, Tunali D, Evrensel T, Manavoglu O. A multi-institutional evaluation of carboplatin plus docetaxel regimen in elderly patients with advanced gastric cancer. J BUON. 2013 Jan-Mar;18(1):147-53. PubMed PMID: 23613400

A22. Olcun Umit Unal, Ilhan Oztop, Nurgul Yasar, Zuhat Urakci, Tahsin Ozatli, Oktay Bozkurt, Alper Sevinc, Yusuf Gunaydin, Burcu Yapar Taskoylu, Erkan Arpaci, Arife Ulas, Hilmi Kodaz, Onder Tonyali, Nilufer Avci, Asude Aksoy, Ahmet Ugur Yilmaz. Clinicopathologic characteristics, treatment outcomes, and prognostic factors of primary thoracic soft tissue sarcoma:A multicenter study of the Anatolian Society of Medical Oncology (ASMO). Thoracic Cancer 2015 Jan;6 (1): 85–90. DOİ: 10.1111/1759-7714.12150

A23. Kocak N, Ustün H, Gülkaç MD, Kanli AO, Borazan A, Yilmaz A. Effects of 1alpha,25-dihydroxyvitamin D3 on doxorubicin-induced chromosomal aberrations in rat bone marrow cells. Acta Oncol. 2004;43(2):204-8. PubMed PMID: 15163171.

A24. Tulay Akman, Ozgur Tanrıverdı, Mehmet A. Ozturk, Ibrahim Petekkaya, Hakan Bakkal, Ozlem U. Sonmez, Nilufer Avcı, Seyda Zengın, Gorkem Aksu, Gokhan Ozyıgıt, Huseyin Abalı. A View from Young Oncologists on Clinical Trials in Turkey: Obstacles and Solution Proposals UHOD 2014;3(24):1-7. DOİ: 10.4999/uhod.14428

A25. Nilüfer Avcı, Mehmet Ali Balcı, İrfan Esen, Gülen Tandoğan, Mustafa Merter, Erdem Çubukçu, Fatih Ölmez, Belkıs Nihan Coşkun, Mustafa Hartavi, Şahsine Tolunay. General Characterıstıcs Of Male Breast Cancer Patıents In Bursa Regıon. The Journal Of Breast Health 2012; 8(3):126-129

A26. Nilüfer Avcı, Mustafa Canhoroz, Özkan Kanat, Mine Sibel Gürün. The Prevalance of Herbal Product Use as a Alternative Medicine Among Cancer Patients in Turkey J Clin Anal Med 2015;6(3): 327-30 DOI: 10.4328/JCAM.2025

A27. Nilüfer Avcı, Arife Ulaş, Çetin Ordu, Taner Aydın, Şahsine Tolunay, Bala Başak, Usta Alioğlu, Ender Kurt, Türkkan Evrensel. Metaplastic Breast Cancer and EGFR Expression J Clin Anal Med 2015;6(5): 616-9 DOI: 10.4328/JCAM.2339

A28. Sinem Çubukçu, Özkan Kanat, Erdem Çubukçu, Ömer Fatih Ölmez, Mustafa Canhoroz, Nilüfer Avcı, Mustafa Hartavi, Adem Deligönül, Serdar Seyhan, Aylin Ayyıldız, Ünal Taşdemir,Osman Manavoğlu. Efficacy of Sunitinib Patients with İmatinib Resistant Gastrointestinal Stromal Tumors. JClinAnal Med 2014;5(4):304-6. DOI:10.4328/JCAM.1375

A29. Ordu Ç, Pilanci KN, Avci N, Yıldız İ, Alço G, Demirhan Ö, Köksal Üİ, Elbüken F, Tecimer C, Demir G, Prognostic Relevance of Sunitinib Toxicities and Comparison of Continuous vs Intermittent Sunitinib Dosing Schedule in Metastatic Renal Cell Cancer Patients, Contemporary Oncology 2014(kabul edildi) DOI: 10.5114/wo.2014.47362

A30. Tanriverdi O, Avci N, Oktay E, Kalemci S, Pilanci KN, Cokmert S, Menekse S, Kocar M, Sen CA, Akman T, Ordu C, Goksel G, Meydan N, Barutca S. Pretreatment Serum Albumin Level is an Independent Prognostic Factor in Patients with Stage IIIB Non-Small Cell Lung Cancer: A Study of the Turkish Descriptive Oncological Researches Group. Asian Pac J Cancer Prev. 2015;16(14):5971-6.

A31.Avci N, Hayar M, Altmisdortoglu O, Tanriverdi O, Deligonul A, Ordu C, Evrensel T. Smoking habits are an independent prognostic factor in patients with lung cancer. Clin Respir J. 2015 Sep 14. doi: 10.1111/crj.12386.

A32. Nayir E, Tanriverdi O, Karakas Y, Kilickap S, Serdar Turhal N, Avci N, Okutur K, Koca D, Erdem D, Abali H, Yamac D, Bilir C, Kacan T. Tendency of cancer patients and their relatives to use internet for health-related searches: Turkish Oncology Group (TOG) Study. J BUON. 2016 May-Jun;21(3):714-9.

A33. Deligonul A, Evrensel T, Avci N, Ugras N, Ture M, Cubukcu E, Hartavi M, Fatih Olmez O, Kurt E, Tolunay S, Kanat O, Manavoglu O. Immunohistochemical expression of human epidermal growth factor receptor (HER)-4 and prognosis in patients with metastatic breast cancer. J BUON. 2016 May-Jun;21(3):564-9.

A34. Tanriverdi O, Menekse S, Teker F, Oktay E, Nur Pilanc K, Gunaldi M, Kocar M, Kacan T, Bahceci A, Avci N, Akman T, Cokmert S, Yesil-Cinkir H, Teoman Yanmaz M. The mean platelet volume may predict the development of isolated bone metastases in patients with breast cancer: a retrospective study of the Young Researchers Committee of the Turkish Oncology Group (TOG). J BUON. 2016 Jul-Aug;21(4):840-850.

A35. Avcı N, Ture M, Deligonul A, Cubukcu E, Olmez OF, Sahinturk S, Topak A, Kurt E, Evrensel T, Şahin AB, Yakut T. Association and Prognostic Significance of the Functional -1562C/T Polymorphism in the Promoter Region of MMP-9 in Turkish Patients with Gastric Cancer. Pathol Oncol Res. 2015 Sep;21(4):1243-7. doi: 10.1007/s12253-015-9950-7. Epub 2015 Jul 9.

A36. Süner A, Aydın D, Hacıoğlu MB, Doğu GG, İmamoğlu GI, Menekşe S, Pilancı KN, Yazıcı ÖK, Koca D, Karaağaç M, Akyol M, Akman T, Ergen S, Avcı N, Kaçan T, Bozkurt O, Kefeli U, Urakçı Z, Araz M, Arpacı E, Harputlu H, Sevinç A. Effectiveness and safety of cabazitaxel chemotherapy for metastatic castration-resistant prostatic carcinoma on Turkish patients (The Anatolian Society of Medical Oncology). Eur Rev Med Pharmacol Sci. 2016 Apr;20(7):1238-43.

A37. Artaç M, Korkmaz L, Coşkun HŞ, Dane F, Karabulut B, Karaağaç M, Çabuk D, Karabulut S, Aykan NF, Doruk H, Avcı N, Turhal NS. Bevacuzimab May Be Less Effective in Obese Metastatic Colorectal Cancer Patients. J Gastrointest Cancer. 2018 Jan 4. doi: 10.1007/s12029-017-0047-2.

A38. Aksoy A, Odabas H, Kaya S, Bozkurt O, Degirmenci M, Topcu TO, Aytekin A, Arpaci E, Avci N, Pilanci KN, Cinkir HY, Bozkaya Y, Cirak Y, Gumus M Hormone receptor status and survival of medullary breast cancer patients. A Turkish cohort. Saudi Med J. 2017 Feb;38(2):156-162. doi: 10.15537/smj.2017.2.18055.


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